SYMPRED consensus secondary structure prediction

Options Help SYMPRED is a consensus -deriving secondary structure prediction program that uses the PSI-BLAST algorithm to produce input for the individual methods used. The consensus is derived through dynamic programming where all predictions are optimally segmented to a high accuracy level prediction. SYMPRED can be run using any combination of PHDpsi (Rost and Sander, 1993), PROFsec (Rost, unpublished), SSPro2.01 (Pollastri et al, 2002), YASPIN (Lin et al, 2005), JNet (Cuff and Barton, 2000) and PSIPred (Jones, 1999). The SYMPRED server is also part of the global automated assessment server EVA (Koh et al, 2003). Reference: Simossis V.A. and Heringa J. (2004) Optimally segmented consensus secondary structure prediction. Bioinformatics (submitted).

Paste in a sequence in FASTA format: Or Upload a FASTA sequence file
Enter a name for your job	Choose a database for PSI-BLAST to use: Help NR SCOP 40
Choose a combination of secondary structure prediction methods to use (min. 2 methods): Help
PHDpsi PROFsec SSPro 2.01 Predator	YASPIN JNet PSIPred
Choose a consensus deriving scheme: Help    Dynamic Programming Majority Voting	Choose a weighting scheme for representing each method: Help No weighting Q3-based weighting SOV-based weighting
(NB: server results have a maximum lifetime of 15 days): Help Also send me the results by email    My email address is

Interface written by Victor A. Simossis and Jaap Heringa