sidebar-main
title
griff
banner-button_0 banner-button_Layer-7 banner_button_03 banner-button_Layer-4 banner-button_05 banner-button_Layer-5 banner-button_07
banner-button_08 banner-button_09 banner-button_10
Bioinformatics Unit banner
   homeoffresearchoffconfoffprogonmemoffpuboffvacoff
   tabfoot tabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bgtabfoot-bg

PRALINE multiple sequence alignment

The recent major upgrade on our compute server, has lead to some configuration issues that turn out to be very hard to resolve.

We are still working on this, and hope to have the server back online in the course of this month (June).

We apologise again for the inconvenience,

and thank you for your continued patience.

Praline

SOAP service (cog WSDL) now available.

PRALINE sample output

References and FAQs

PRALINE is a multiple sequence alignment program with many options to optimise the information for each of the input sequences; e.g. homology-extended alignment, predicted secondary structure and/or transmembrane structure information and iteration capabilities.

 
Paste in your PROTEIN sequences in FASTA format (MAX 500 sequences, length 2000):
Or upload a FASTA file (MAX 500 sequences, length 2000):
Enter a name for your job:
 Options
Exchange weights matrix:
Associated gap penalties:
 Help Open Extension  Help
Progressive alignment strategy:  Help
  PSI-BLAST Iterations at an E-value cut-off of  DB
at a score cut-off of  Iterations
Structural features:  Help
  DSSP-defined secondary structure search     Help
  Secondary structure prediction   Help
  Transmembrane structure prediction   Help
Output customization:
  Tree representation final alignment     Help
  Customize alignment colours     Help
  File format final alignment       Help
 E-mail
E-mail me when when my job is done at:
 Submit
 

(c) IBIVU 2025. If you are experiencing problems with the site, please contact the webmaster.