PRALINE sequence alignment results for job Example_3

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PRALINE Iteration 0 The PRALINE alignment process was completed in 74.0 seconds. Alignment score = 217150.00 Alignment score per aligned residue pair = 8.61 Sequence identities = 4845 Percent sequence identity = 0.19 Number of sequences = 12 Alignment length = 471 Number of residues = 4896 Number of gaps = 756 The alignment iterations halted at iteration 1 out of 5 requested. Your alignments have converged. Iteration 1

Download the final alignment [p450.msf] Download PRALINE raw output file [results.out] Download this iteration's alignment [p450_0.msf]

Results colour-coded for amino acid conservation The current colourscheme of the alignment is for amino acid conservation.

The conservation scoring is performed by PRALINE. The scoring scheme works from 0 for the least conserved alignment position, up to 10 for the most conserved alignment position. The colour assignments are: Unconserved 0 1 2 3 4 5 6 7 8 9 10 Conserved   . . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 1n97a m k r l s l r e a w p y l k d l q q d p l a v l l a w g r a h p r l f l p l p r f p l a - - - - - - 1gwia - - - - - - - - - - - - - - - - - - a r i p l d p f v t d l d g e s a r l r a a g p l a a v e l p g 1jipa - - - - - - - - - - - - - - - t t v p d l e s d s f h v d w y r t y a e l r e t a p v t p v r f l - 1jfba - - - - - - - - - - - - - - - - a p s f p f s r a s g p e p p a e f a k l r a t n p v s q v k l f d 1cpt - - - m d a r a t i p e h i a r t v i l p q g y a d d e v i y p a f k w l r d e q p l a m a h i e g 1n40a - - - - - - - - - - - - - - a t v l l e v p f s a r g d r i p d a v a e l r t r e p i r k v r t i t 1lfka - - - - - - - - - - - - - - - - - - - d p r p l h i r r q g l d p a d e l l a a g a l t r v t - - - 1qmqa a n l a p l p p h v p e h l v f d f d m y n p s n l s a g v q e a w a v l q e s n v p d l v w t r c 1io7a - - - - - - - - - - - - - - - - - - - - - - - - - - - - - m y d w f s e m r k k d p v y y - - - - - 1jpza - t i k e m p q p k t f g e l k n l p l l n t d k p v q a l m k i a d e l g e i f k f e a p g r v t 1e9xa m s a v a l p r v s g g h d e h g h l e e f r t d p i g l m q r v r d e c g d v g t f q l a g k q v 1dt6a - - - - - p p g p t p f p i i g n i l q i d a k d i s k s l t k f s e c y g p v f t v y l g m k p t Consistency 0 0 0 0 0 1 1 0 0 0 1 0 0 0 1 1 2 2 2 2 3 2 2 2 2 2 2 2 2 4 3 3 3 3 4 4 6 4 4 4 3 5 5 3 3 3 2 2 1 1     . . . . . . . . . 60 . . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 1n97a - - - - - l i f d p e g v e g a l l a e g t t k a t f q y r a l s - - - - - - - - - - - - - - - r l 1gwia g v p v w a v t h h a e a k a l l t d p r l v k d i n v w g a w r r g e i p a - - d w p l i g l a n 1jipa g q d a w l v t g y d e a k a a l s d l r l s s d p k k k y p g v e v e f p a y l g f p e d v r n y 1jfba g s l a w l v t k h k d v c f v a t s e k l s k v r t r q g f p e l s a s g k - - - - - - - q a a k 1cpt y d p m w i a t k h a d v m q i g k q p g l f s n a e g s e i l y d q n n e a f m r s i s g g c p h 1n40a g a e a w l v s s y a l c t q v l e d r r f s m k e t a a a g a p r l n - - - - - - - - - - a l t v 1lfka a e t h w m a t a h a v v r q v m g d h q q f s t r r r w d - - - - - - - - - - - - - - - - - - p e 1qmqa n g g h w i a t r g q l i r e a y e d y r h f s s e c p f i p r e a g - - - - - - - - - - - - - e a 1io7a d g n i w q v f s y r y t k e v l n n f s k f s s d l t g y h e r l e d l r n - - - g k i r f d i p 1jpza r y l s s q r l i k e a c d e s r f d k n l s q a l k f v r d f a - g d g l f t s w t h e k n w k k 1e9xa v l l s g s h a n e f f f r a g d d d l d q a k a y p f m t p i f - g e g v v f d a s p e r r k e m 1dt6a v v l h g y e a v k e a l v d l g e e f a g r g s v p i l e k v s k g l g i a f s n a k t w k e m r Consistency 2 2 2 3 5 4 4 5 3 4 4 3 4 4 4 5 3 3 6 2 4 3 4 5 4 3 2 2 2 2 2 2 2 1 2 2 1 1 1 0 0 0 1 1 1 0 1 1 3 3     . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 1n97a t g r g l l t d w g e s w k e a r k a l k d p f l p k n v r g y r e a m e e e a r a f f g e w r g e 1gwia p g r s m l t v d g a e h r r l r t l v a q a l t v r r v e h m r g r i t e l t d r l l d e l p a d 1jipa f a t n m g t s d p p t h t r l r k l v s q e f t v r r v e a m r p r v e q i t a e l l d e v - g d 1jfba a k p t f v d m d p p e h m h q r s m v e p t f t p e a v k n l q p y i q r t v d d l l e q m k q k 1cpt v i d s l t s m d p p t h t a y r g l t l n w f q p a s i r k l e e n i r r i a q a s v q r l l d f 1n40a p p e v v n n m g n i a d a g l r k a v m k a i t - p k a p g l e q f l r d t a n s l l d n l i t e 1lfka l v g n l m d y d p p e h t r l r r k l t p g f t l r k m q r m a p y i e q i v n d r l d e m e r a 1qmqa y d f i p t s m d p p e q r q f r a l a n q v v g m p v v d k l e n r i q e l a c s l i e s l r p q 1io7a t r y t m l t s d p p l h d e l r s m s a d i f s p q k l q t l e t f i r e t t r s l l d s i d p - 1jpza a h n i l l p s f s q q a m k g y h a m m v d i a v q l v q k w e r l n a d e h i e v p e d m t r l 1e9xa l h n - - - a a l r g e q m k g h a a t i e d q v r r m i a d w g e - - - a g e i d l l d f f a e l 1dt6a r f s l m t l r n f g m g k r s i e d r i q e e a r c l v e e l r k t n - a s p c d p t f i l g c a Consistency 3 2 3 3 5 3 4 4 4 4 4 4 4 4 4 3 6 4 4 4 4 4 3 5 4 3 4 4 7 5 3 5 5 4 2 5 3 5 4 4 3 5 5 6 5 4 6 2 3 2     . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 1n97a - - - - - e r d l d h e m - - - - - - - - - - l a l s l r l l g r a l f g k p l s p s l a e h a l k 1gwia g - - - g v v d l k a a f a - - - - - y p l p m y v v a d l m g i e e a r l p r l - k v l f e k f f 1jipa s - - - g v v d i v d r f a - - - - - h p l p i k v i c e l l g v d e k y r g e f g r w s s e i l v 1jfba g c a n g p v d l v k e f a - - - - - l p v p s y i i y t l l g v p f n d l e y l - t q q n a i r t 1cpt d - - - g e c d f m t d c a - - - - - l y y p l h v v m t a l g v p e d d e p l m l k l t q d f f - 1n40a g - - - a p a d l r n d f a - - - - - d p l a t a l h c k v l g i p q e d g p k l f r s l s i a f m 1lfka g - - - s p a d l i a f v a - - - - - d k v p g a v l c e l v g v p r d d r d m f - m k l c h g h l 1qmqa - - - - g q c n f t e d y a - - - - - e p f p i r i f m l l a g l p e e d i p h l k y l t d q m t - 1io7a - - - - r e d d i v k k l a - - - - - v p l p i i v i s k i l g l p i e d k e k f - k e w s d l v a 1jpza t l d t i g l c g f n y r f n s f y r d q p h p f i t s m v r a l d e a m n k l q r a n p d d p a y 1e9xa t i y t s s a c l i g k k f - - - - r d q l d g r f a k l y h e l e r g t d p l a y v d p y l p i e 1dt6a p c n v i c s v i f h n r f - - - - - d y k d e e f l k l m e s l h e n v e l l g t p l d y f p g i Consistency 2 0 0 0 3 3 4 5 6 3 3 3 3 5 0 0 0 0 0 3 3 3 4 3 3 7 4 3 3 6 4 7 6 4 4 4 3 3 4 4 4 1 3 3 3 3 3 3 3 2     . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 1n97a a l d r i m a q t r s p l a l l d l a a e a r f r k d r g a l y - - r e a e a l i v h p p l s - - - 1gwia s t q t p p e e v v a t l t e l a s i m t d t v a a k r a a p g - - d d l t s a l i q a s e n g d - 1jipa m d p e r a e q r g q a a r e v v n f i l d l v e r r r t e p g - - d d l l s a l i r v q d d d d g 1jfba n g s s t a r e a s a a n q e l l d y l a i l v e q r l v e p k - - d d i i s k l c t e q v k p g - 1cpt - g v e a a r r f h e t i a t f y d y f n g f t v d r r s c p k - - d d v m s l l a n s k l d g n - 1n40a s s a d p i p a a k i n w d r d i e y m a g i l e n p n i t t g - - l m g e l s r l r k d p a y s - 1lfka d a s l s q k r r a a l g d k f s r y l l a m i a r e r k e p g - - e g m i g a v v a e y g d - - - 1qmqa - r p d g s m t f a e a k e a l y d y l i p i i e q r r q k p g - - t d a i s i v a n g q v n g r - 1io7a f r l g k p g e i f e l g k k y l e l i g y v k d - - h l n s g - - t e v v s r v v n s n - - - - - 1jpza d e n k r q f q e d - - i k v m n d l v d k i i a d r k a s q s d - d l l t h m l n g k d p e t g e 1e9xa s f r r r d e a r n g l v a l v a d i m n g r i a n p p t d k s d r d m l d v l i a v k a e t g t p 1dt6a h k t l l k n a d y i k n f i m e k v k e h q k l l d v n n p r - - d f i d c f l i k m e q e n n l Consistency 2 3 3 3 3 3 3 5 3 3 3 3 3 3 4 5 3 4 5 5 3 2 4 5 4 3 4 4 3 4 5 4 0 0 5 3 5 4 4 4 7 5 3 4 4 2 4 2 2 0     . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300 1n97a h l p r e r a l s e a v t l l v a g h e t v a s a l t w s f l l l s h r p d w q k r v a e s e e a a 1gwia h l t d a e i v s t l q l m v a a g h e t t i s l i v n a v v n l s t h p e q r a l v l s g e a e w 1jipa r l s a d e l t s i a l v l l l a g f e s s v s l i g i g t y l l l t h p d q l a l v r r d p s a l 1jfba n i d k s d a v q i a f l l l v a g n a t m v n m i a l g v a t l a q h p d q l a q l k a n p s l a 1cpt y i d d k y i n a y y v a i a t a g h d t t s s s s g g a i i g l s r n p e q l a l a k s d p a l i 1n40a h v s d e l f a t i g v t f f g a g v i s t g s f l t t a l i s l i q r p q l r n l l h e k p e l i 1lfka d a t d e e l r g f c v q v m l a g d d n i s g m i g l g v l a m l r h p e q i d a f r g d e q s a 1qmqa p i t s d e a k r m c g l l l v g g l d t v v n f l s f s m e f l a k s p e h r q e l i e r p e r i 1io7a - l s d i e k l g y i i l l l i a g n e t t t n l i s n s v i d f t r f - - n l w q r i r e e n l y 1jpza p l d d e n i r y q i i t f l i a g h e t t s g l l s f a l y f l v k n p h v l q k a a e e a a r v 1e9xa r f s a d e i t g m f i s m m f a g h h t s s g t a s w t l i e l m r h r d a y a a v i d e l d e l 1dt6a e f t l e s l v i a v s d l f g a g t e t t s t t l r y s l l l l l k h p e v a a r v q e e i e r v Consistency 3 6 5 4 5 4 5 4 3 3 3 4 4 6 6 4 9 * 3 5 7 5 5 5 4 6 4 3 6 6 5 3 8 5 5 5 7 5 3 4 4 4 5 3 5 5 4 5 4 5     . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 1n97a - - - - - - - - - - - - - - - - - - l a a f q e a l r l y p p a w - i l t r r l e r p l l l g e d r 1gwia - - - - - - - - - - - - - - - - - - s a v v e e t l r f s t p t s h v l i r f a a e d v p v g d r v 1jipa - - - - - - - - - - - - - - - - - - p n a v e e i l r y i a p p e - t t t r f a a e e v e i g g v a 1jfba - - - - - - - - - - - - - - - - - - p q f v e e l c r y h t a s a l a i k r t a k e d v m i g d k l 1cpt - - - - - - - - - - - - - - - - - - p r l v d e a v r w t a p v k - s f m r t a l a d t e v r g q n 1n40a - - - - - - - - - - - - - - - - - - p a g v e e l l r i n l s f a d g l p r l a t a d i q v g d v l 1lfka - - - - - - - - - - - - - - - - - - q r a v d e l i r y l t v p y s p t p r i a r e d l t l a g q e 1qmqa - - - - - - - - - - - - - - - - - - p a a c e e l l r r f s l v - - a d g r i l t s d y e f h g v q 1io7a - - - - - - - - - - - - - - - - - - l k a i e e a l r y s p p v m - r t v r k t k e r v k l g d q t 1jpza l v d - p v p s y k q v k q l k y v g m v l n e a l r l w p t a p a f s l y a k e d t v l g g e y p 1e9xa y g d g r s v s f h a l r q i p q l e n v l k e t l r l h p p l i i l m r v a k g e f e v - q g h r 1dt6a i g r h r s p c m q d r s r m p y t d a v i h e i q r f i d l l p t n l p h a v t r d v r f r n y f Consistency 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 5 6 6 * 5 6 * 4 3 4 4 4 2 1 3 4 3 6 3 5 4 5 5 5 3 4 5 5 3 3     . . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 1n97a l p p g t t l v l s p y v t q r l h f p d g e a f - - r p e r f l e e r g t p s g r - - - - - - - - 1gwia i p a g d a l i v s y g a l g r - - - - d e r a h g p t a d r f d l t r t - s g n r - - - - - - - - 1jipa i p q y s t v l v a n g a a n r - - - - d p k q f - p d p h r f d v t r - - d t r g - - - - - - - - 1jfba v r a n e g i i a s n q s a n r - - - - d e e v f - e n p d e f n m n r k w p p q d - - - - - - - - 1cpt i k r g d r i m l s y p s a n r - - - - d e e v f - s n p d e f d i t r - - f p n r - - - - - - - - 1n40a v r k g e l v l v l l e g a n f - - - - d p e h f - p n p g s i e l d r p - n p t s - - - - - - - - 1lfka i k k g d s v i c s l p a a n r - - - - d p a l a - p d v d r l d v t r - - e p i p - - - - - - - - 1qmqa l k k g d q i l l p q m l s g l - - - - d e r e n - a a p m h v d f s r - - q k v s - - - - - - - - 1io7a i e e g e y v r v w i a s a n r - - - - d e e v f - h d g e k f i p d r - - n p n p - - - - - - - - 1jpza l e k g d e l m v l i p q l h r - - - - d k t i w g d d v e e f r p e r f e n p s a - - - i p q h a 1e9xa i h e g d l v a a s p a i s n r - - - - i p e d f - p d p h d f v p a r y e q p r q e d l l n r w t 1dt6a i p k g t d i i t s l t s v l h - - - - d e k a f - p n p k v f d p g h f - l d e s g n f k k s d y Consistency 8 4 5 7 6 3 8 6 5 5 3 3 4 6 5 6 0 0 0 0 8 5 5 4 5 0 4 5 5 4 4 7 4 3 4 8 0 0 3 5 3 4 0 0 0 0 0 0 0 0     . . . . . . . . . 410 . . . . . . . . . 420 . . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 1n97a y f p f g l g q r l c l g r d f a l l e g p i v l r a f f r r f r l d p l p f p r v l - - - - a q v 1gwia h i s f g h g p h v c p g a a l s r m e a g v a l p a l y a r f p h l d l a v p a a e l r n k p v v 1jipa h l s f g q g i h f c m g r p l a k l e g e v a l r a l f g r f p a l s l g i d a d d v v w r r s l 1jfba p l g f g f g d h r c i a e h l a k a e l t t v f s t l y q k f p d l k v a v p l g k i n y t p l n 1cpt h l g f g w g a h m c l g q h l a k l e m k i f f e e l l p k l k s v e l s g p p r l v - - - a t n 1n40a h l a f g r g q h f c p g s a l g r r h a q i g i e a l l k k m p g v d l a v p i d q l v w r t r f 1lfka h v a f g h g v h h c l g a a l a r l e l r t v f t e l w r r f p a l r l a d p a q d t e f r l t t 1qmqa h t t f g h g s h l c l g q h l a r r e i i v t l k e w l t r i p d f s i a - p g a q i q h k s g - 1io7a h l s f g s g i h l c l g a p l a r l e a r i a i e e f s k r f r h i e i l - d t e k v - - - p n e 1jpza f k p f g n g q r a c i g q q f a l h e a t l v l g m m l k h f d f e d h t n y e l d i k e t l t l 1e9xa w i p f g a g r h r c v g a a f a i m q i k a i f s v l l r e y e - - - - f e m a q p p e s y r n d 1dt6a f m p f s a g k r m c v g e g l a r m e l f l f l t s i l q n f k l - - - q s l v e p k d l d i t a Consistency 5 5 4 * 9 3 * 3 7 4 * 5 9 5 3 7 8 5 5 8 4 3 6 4 6 4 5 6 5 4 6 7 4 2 3 3 4 4 2 4 4 3 3 4 2 1 2 3 4 2     . . . . . . . . . 460 . . . . . . . . . 470 . 1n97a t l r p e g g l p a r p r e - - - - - - - 1gwia t q n d l f e l p v r l a h h - - - - - - 1jipa l l r g i d h l p v r l d g - - - - - - - 1jfba r d v g i v d l p v i f - - - - - - - - - 1cpt f v g g p k n v p i r f t k a - - - - - - 1n40a q r r i p e r l p v l w - - - - - - - - - 1lfka p a y g l t e l m v a w - - - - - - - - - 1qmqa i v s g v q a l p l v w d p a t t k a v - 1io7a v l n g y k r l v v r l k s - - - - - - - 1jpza k p e g f v v k a k s k k i p l g g i - - 1e9xa h s k m v v q l a q p a c v r y r r r t - 1dt6a v v n g f v s v p p s y q l c f i p i h h Consistency 3 3 3 5 3 3 3 7 6 5 4 3 1 1 0 0 0 0 0 0 0   (c) IBIVU 2025. 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